BDBM429772 (5R)-5-[3-[4- (4,5-dichloro- 2-methoxy- phenyl)-1- piperidyl]-3- oxo-propyl]-5- methyl- imidazolidine- 2,4-dione::US10550100, Compound 96

SMILES COc1cc(Cl)c(Cl)cc1C1CCN(CC1)C(=O)CC[C@@]1(C)NC(=O)NC1=O

InChI Key InChIKey=DVNZZKYEMTZGSP-LJQANCHMSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 429772   

TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM429772((5R)-5-[3-[4- (4,5-dichloro- 2-methoxy- phenyl)-1-...)
Affinity DataIC50: >100nMAssay Description:The basis for the assay is the cleavage of the substrate 390 MMP FRET Substrate I (Anaspec Cat# AS-27076) by human MMP14 (Biomol, Cat#SE-259).For the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent